Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Jade Scientific, Inc Formic acid, 50ml, 64-18-6
Formic acid. For mass spectrometry, ca. 98%~98%. Glass Bottle. For Research Only
Sigma Aldrich Fine Chemicals Biosciences Formic acid, 64-18-6, MFCD00003297, 1 L
Linear Formula: HCOOH, Molecular Weight: 46.03, reagent grade, ≥95%.
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Supply Solutions Sigma Aldrich - Formic acid puriss. p.a., for mass spectroscopy, 250ml .CAS Number: [000064-18-6]; Size: 250ml; CAS Number: 64-18-6
Sigma Aldrich - Formic acid puriss. p.a., for mass spectroscopy, 250ml .CAS Number: [000064-18-6]; Size: 250ml; CAS Number: 64-18-6
U.S. Pharmacopeia Formic Acid (1.2 mL/ampule; 3 ampules) | 64-18-6 | MFCD00003297
Formic Acid (1.2 mL/ampule; 3 ampules) | Mol Wt: 46.025 | 64-18-6 | MFCD00003297 |
Sigma Aldrich Fine Chemicals Biosciences Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | 64-18-6 | MFCD00003297 | 1L
Formic acid puriss., meets analytical specifications of DAC, FCC, 98.0-100% | Purity: 98.0-100% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1L
Medchemexpress LLC GZD856 formic | 2804039-78-7 | 95.4% | 578.58 g/mol | C30H29F3N6O3 | 1 ML
GZD856 formic is a research-grade small-molecule inhibitor supplied as a 10 mM solution in DMSO for laboratory use. It is provided as the formic salt in a 1 mL vial and is intended for in vitro and exploratory studies needing a pre-dissolved, characterized compound.
- Pre-formulated 10 mM solution for immediate use.
- Supplied in a 1 mL vial for small-scale experiments.
- Formic salt form to enhance solubility and stability.
- Purity determined by HPLC, reported at 95.36%.
- Molecular weight 578.58 g/mol; formula C30H29F3N6O3.
Sigma Aldrich Fine Chemicals Biosciences Formic acid ACS reagent, >=88% | 64-18-6 | MFCD00003297 | 2.5L
Formic acid ACS reagent, >=88% | Purity: >=88% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 2.5L
Sigma Aldrich Fine Chemicals Biosciences Formic acid | 64-18-6 | MFCD00003297 | 100mL
Formic acid | Purity: ≥88% | MW:46.03 | 64-18-6 | MFCD00003297 | 100mL
eMolecules Oakwood Chemicals Formic Acid 1kg 480142339 080324 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Oakwood Chemicals Formic Acid 1kg 480142339 080324 0 000 64-18-6 MFCD00003297 46 025 CH2O2
Medchemexpress LLC Ammonium formate | 540-69-2 | MFCD00013103 | 98.5% | 63.06 g/mol | CH5NO2 | 50g
Formic acid ammonium salt is an endogenous metabolite
Medchemexpress LLC Lcc-12 formic | 3029253-76-4 | 99.2% | 460.57 g/mol | C18H40N10O4 | 10 MG
LCC-12 formic is a research-grade small molecule probe (a dimer of metformin) used to modulate mitochondrial copper(II) and study inflammation and metabolic pathways in cellular and animal models.
- Targets mitochondrial copper(II) and reduces the NAD(H) pool.
- Reduces inflammation in mouse models of bacterial and viral infection.
- Serves as a tool to study metabolic disease, cell plasticity, and epigenetic programming.
- High purity and characterized molecular properties for reliable experimental use.
- Compatible with storage at -20°C; in solution store at -80°C for long-term stability.
Medchemexpress LLC Bisindolylmaleimide IX formic | 00-00-0 | 96.0% | C26H25N5O4S | 10MG
Ro 31-8220 formic is a small-molecule research reagent that acts as a potent, cell-permeable inhibitor of protein kinase C (PKC) and several other kinases. It is used in biochemical and cellular studies to probe PKC-dependent signaling, kinase selectivity, and downstream pathway effects such as JNK activation and c-Jun induction.
- Potent PKC inhibition with low-nanomolar IC50s.
- Inhibits multiple kinases for broad pathway interrogation.
- Cell-permeable for use in cellular assays.
- High purity solid with characteristic orange to red color.
- Stable when stored sealed at -20°C; in solvent can be stored at -80°C for extended periods.
- Available in small milligram pack sizes suitable for research use.