Formic Acid
Formic acid (HCOOH) is naturally-occurring, flammable, corrosive, organic, and the simplest carboxylic acid. Used as a hydride ion source in synthetic organic chemistry, a mobile phase component in HPLC, a preservative/antibacterial agent in agriculture, etc.
Formic or methanoic acid (CAS: 64-18-6; PubChem ID: 284) is a colorless organic acid with the formula HCOOH. At ambient temperatures, it has a strong, penetrating odor, like acetic acid. Used in chemical synthesis as an intermediate, this simple carboxylic acid is miscible in water and most organic solvents and is somewhat hydrocarbon-soluble.
Formic acid occurs naturally in the venom of some ants and bees. Formate, the conjugate base of formic acid, also occurs naturally in bodily fluids following methanol poisoning.
Formic acid is a source of hydride ion in synthetic organic chemistry, as in the Eschweiler-Clarke and Leuckart-Wallach reactions. It is also a useful component of the mobile phase in reversed-phase high-performance liquid chromatography (RP-HPLC) for peptides, proteins, and intact viruses.
Although formic acid is easily metabolized and eliminated, it can have toxic effects. Methanol metabolism produces formic acid and formaldehyde, which are responsible for the optic nerve damage that results from methanol poisoning. Chronic exposure in humans may cause kidney damage and skin allergies in some people.
In diluted forms, formic acid and formate esters are used as artificial flavorings and perfume additives. In higher concentrations, formic acid is flammable, and skin and eye contact with concentrated liquid or vapors is dangerous.
In agriculture, formic acid is used as a preservative and antibacterial agent and by beekeepers to kill mites. It is useful in leather tanning, textile dyeing and finishing, and in rubber production. Formic acid replaces mineral acids in limescale removers and other cleaning products.
Sigma Aldrich Fine Chemicals Biosciences SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES
NC3982132 FORMIC ACID 98-100 FOR HPLC L
Sigma Aldrich Fine Chemicals Biosciences Formic acid, 64-18-6, MFCD00003297, 500 mL
Linear Formula: HCOOH, Molecular Weight: 46.03, puriss., meets analytical specifications of DAC, FCC, 98.0-100%.
U.S. Pharmacopeia PROIONIC ACID 1.5ML AMPULES
Propionic Acid (1.5 mL/ampule; 3 ampules)U S PHARMACOPEIA mfg# 1572208
Medchemexpress LLC SLB1122168 formic | C23H37N3O3 | 10 MM * 1 ML
SLB1122168 formic is a potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM. It is intended for research use only and available in various forms, including solid and as a 10 mM * 1 mL solution in DMSO.
- Potent Spns2-mediated S1P release inhibitor with an IC50 of 94 nM
- Intended for research use only
- Purity of 99.91%
- Molecular weight of 403.56
- Appears as an off-white to light yellow solid
- Soluble in DMSO at 100 mg/mL (247.79 mM)
- Induces a dose-dependent decrease in circulating lymphocytes in vivo
- Achieves a maximum concentration of 4 μM in rats at 2 hours post-dose with a half-life of 8 hours
- Related to respiratory, inflammatory, and pulmonary diseases, and lung fibrosis
- Affects inflammation/immunology, GPCR/G protein, and LPL receptor signaling pathways
Sigma Aldrich Fine Chemicals Biosciences Formic acid | 64-18-6 | MFCD00003297 | 1 L
Formic acid | Purity: 98% | Mol Wt: 46.03 | 64-18-6 | MFCD00003297 | 1 L
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 1 ML
PKCiota-IN-2 formic is a potent PKCiota (PKC-ι) inhibitor with an IC50 of 2.8 nM. It also inhibits PKC-α and PKC-ε with IC50s of 71 nM and 350 nM, respectively.
- Potent PKCiota inhibitor with an IC50 of 2.8 nM.
- Also inhibits PKC-α with an IC50 of 71 nM.
- Inhibits PKC-ε with an IC50 of 350 nM.
Medchemexpress LLC PKCiota-IN-2 formic | 99.0% | 402.36 | 100 MG
PKCiota-IN-2 formic is a potent inhibitor of PKCiota (PKC-ι) with an IC50 of 2.8 nM. It also demonstrates inhibitory activity against PKC-α and PKC-ε.
- Potent PKCiota (PKC-ι) inhibitor.
- Inhibits PKC-α and PKC-ε.
- Available in solid and solution forms.
- Purity: 99.04%.
- For research use only.
eMolecules 64-18-6 | Formic Acid, ACS Grade | Oakwood Chemicals | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 2.5kg | 480143864
Formic Acid, ACS Grade | Oakwood Chemicals | 64-18-6 | MFCD00003297 | 46.025 | CH2O2 | 88.000 | OC=O | 2.5kg | 480143864